Pharmaceutical Dosage Forms_ Capsules-CRC Press (2018)

Category: Medical

Tag: Medical/Medicine


Posted on 2020-11-30, by lhthang1990.

Description

Invented more than 160 years ago, the capsule today is second only to the compressed tablet among solid dosage in frequency of utilization for drug delivery, and its utilization is growing. According to one estimate,* approximately 10–15% of FDA-approved drugs in 2014 were capsule formulations, about double that in 2007. Originally intended to mask the unpleasant taste of certain medications, today there are many other advantageous reasons and drivers for selecting the capsule for drug delivery, as discussed in the various chapters of this book. Despite the growing utilization of the capsule and the important roles it plays as a dosage form, the capsule has been relatively underserved in the literature. To our knowledge, there have been only two prior published edited texts†,‡
devoted entirely to capsules, the most recent of which was published about 12 years ago. These books were intended to fulfll the need to provide in one place a concise summary of the making and flling of capsules, and of developing formulations for capsules. We are honored to have the opportunity to join the efforts of these prior editors in providing an updated discussion and description of capsule formulation and flling technology and the role of capsules in drug delivery. We are especially honored that Fridrun Podczeck, Brian E. Jones, and J. Michael Newton, editors and/or authors of chapters of those earlier books, have also contributed to this book.

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