Five-Lipoxygenase Products in Asthma (Lung Biology in Health & Disease) (Lung Biology in Health and Disease)

Five-Lipoxygenase Products in Asthma offers an authoritative examination of the biochemistry, basic pharmacology, and clinical pharmacology of the leukotrienes with special emphasis on their role in asthma. A critical reference for every asthma researcher and clinician, Five-Lipoxygenase Products in Asthma · highlights agents and products of the 5-LO pathway and its relationship to other pathways · explores the enzymology of the 5-LO pathway with focus on leukotriene transport, degradation, and excretion · details the role of protein identification in the 5-LO pathway · describes human cell types that produce leukotrienes and their activation · outlines pharmacological and binding study evidence for leukotriene receptors · discusses the recovery of leukotrienes in lung disease · analyzes leukotriene receptor antagonists and synthesis inhibitors by specific agent · provides a by entity summary of individual drug information in exercise-induced, allergen-induced, aspirin-induced, and chronic stable asthma · profiles the use of agents active on the 5-LO pathway in asthma treatment · and more! With complete discussions of the recovery of leukotrienes in induced and spontaneous asthma and other conditions, Five-Lipoxygenase Products in Asthma, will benefit pulmonologists and pulmonary disease specialists; clinical allergists; internists; chest, intensive care, primary care, and family practice physicians; respiratory therapists; physiologists; pathologists; cell and molecular biologists; and graduate and medical school students in these disciplines.