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Annual Review of Genomics and Human Genetics: 2003
David Page, Eric Lander, Richard Lifton | Annual Reviews | 2011-09-30 | 1 pages | English | PDF

In the vertebrate embryo, complex signaling pathways coordinate the establishment of the dorsal-ventral, anterior-posterior, and left-right (L-R) axes. Although vertebrates are bilaterally symmetric externally, most internal organs are asymmetrically oriented with respect to the L-R axis, and this orientation is highly conserved across species...

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