The Serotonin Receptors: From Molecular Pharmacology to Human Therapeutics (The Receptors)

Description

The Serotonin Receptors: From Molecular Pharmacology to Human Therapeutics (The Receptors)

Publisher: Humana Press
Number Of Pages: 640
Publication Date: 2006-06-01
Sales Rank: 916870
ISBN / ASIN: 1588295680
EAN: 9781588295682
Binding: Hardcover
Manufacturer: Humana Press
Studio: Humana Press

A comprehensive, state-of-the-art review of our current understanding of the molecular and structural biology of 5-HT receptors and their potential use freeduan.com for drug discovery. The authors describe the anatomical, cellular, and subcellular distribution of 5-HT receptors and demonstrate a powerful approach to elucidating their physiological role using knockout mice in which the 5-HT receptors were deleted. They also review our understanding of the physiological role(s) of 5-HT receptors based mainly on studies performed in genetically engineered mice. Highlights include discussions of the behavioral phenotypes of 5-HT receptor knockout animals, the molecular biology and pharmacology of 5-HT receptors, and insights into the complexity of 5-HT receptor signal transduction.

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