The Role of DNA Damage and Repair in Cell Aging (Advances in Cell Aging and Gerontology)

Description

Aging occurs at the level of individual cells, a complex interplay between intrinsic "programming" and exogenous "wear and tear", with genetically-determined cellular capacity to repair environmentally-induced DNA damage playing a central role in the rate of aging and its specific manifestations. In 12 chapters, "The Role of DNA Damage and Repair in Cell Aging" provides an intellectual framework for aging of mitotic and post-mitotic cells, describes a variety of model systems for further studies, and reviews current concepts of DNA responses and their relationship to the phenomenon of aging.

As part of a series entitled "Advances in Cell Aging and Gerontology," this volume also summarizes seminal recent discoveries such as the molecular basis for Werner syndrome (a mutant DNA helicase), the complementary roles of telomere shortening and telomerase activity in cell senescence versus immortalization, the role of apoptosis in the homeostasis of aging tissue, and the existence of an inducible SOS-like response in mammalian cells that minimizes DNA damage from repeatedly encountered injurious environmental agents. Insights into the relationship between cellular aging and age-associated diseases, particularly malignancies, are also provided in several chapters.

Disclaimer:
Contents of this page are indexed from the Internet. All actions are under your responsability. Email us to report illegal contents or external links and we'll remove them immediately.

Please check the description for download links if any or do a search to find alternative books.

Can't Download?
Please search mirrors if you can't find download links for "The Role of DNA Damage and Repair in Cell Aging (Advances in Cell Aging and Gerontology)" in "Description" and someone else may update the links. Check the comments when back to find any updates.

Search Mirrors
Maybe some mirror pages will be helpful, search this book at top of this page or click here to find more info.

1. Ebooks list page : 3097
2. Recent Advances in Psychology and Aging, Volume 15 (Advances in Cell Aging and Gerontology) by P. Costa (Repost)
3. Programmed Cell Death, Volume I (Advances in Cell Aging and Gerontology)
4. Genetic Aberrancies and Neurodegenerative Disorders (Advances in Cell Aging and Gerontology)
5. Bacterial Cell-to-Cell Communication: Role in Virulence and Pathogenesis (Advances in Molecular and Cellular Microbiology)
6. Life-Span Extension: Single-Cell Organisms to Man (Aging Medicine)
7. Caspases: Their Role in Cell Death and Cell Survival (Molecular Biology Intelligence Unit)
8. Caspases: Their Role in Cell Death and Cell Survival (Molecular Biology Intelligence Unit)
9. Voices and Visions of Aging: Toward a Critical Gerontology
10. Development and Aging of the Vertebrate Visual System: Special Issue, Neuroembryology and Aging 2006/2007
11. Handbook of the Psychology of Aging, Sixth Edition (Handbooks of Aging)
12. Neurobehavior of Language and Cognition: Studies of Normal Aging and Brain Damage by Lisa Tabor Connor
13. The Biology of the Pancreatic Beta-Cell (Advances in Molecular and Cell Biology) by: S.L. Howell
14. Aging of the Genome: The Dual Role of DNA in Life and Death
15. Aging of the Genome: The Dual Role of DNA in Life and Death
16. Aging of the Genome: The Dual Role of DNA in Life and Death