Genomic Disorders: The Genomic Basis of Disease

Description

Genomic Disorders: The Genomic Basis of Disease

Publisher: Humana Press
Number Of Pages: 448
Publication Date: 2006-04-15
Sales Rank: 1958877
ISBN / ASIN: 1588295591
EAN: 9781588295590
Binding: Hardcover
Manufacturer: Humana Press
Studio: Humana Press

A grand summary and synthesis of the tremendous amount of data now available in the post genomic era on the structural features, architecture, and evolution of the human genome. The authors demonstrate how such architectural features may be important to both evolution and to explaining the susceptibility to those DNA rearrangements associated with disease. Technologies to assay for such structural variation of the human genome and to model genomic disorders in mice are also presented. Two appendices detail the genomic disorders, providing genomic features at the locus undergoing rearrangement, their clinical features, and frequency of detection.

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